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Discontinue Ozempic at least two months before planned pregnancy, and inform surgical teams of use to allow appropriate perioperative planning
The MHRA and EMA include pancreatitis warnings in prescribing information, though current evidence suggests benefits generally outweigh risks in appropriately selected patients
However, adjustments may be considered if: Glycaemic targets are not achieved : Your doctor may increase to the next available dose strength Intolerable side effects persist : A temporary dose reduction or slower titration may be appropriate Weight loss plateaus (for weight management indications): Dose optimisation may be discussed Renal function changes : Monitoring may be increased, though most GLP-1s don't require dose adjustment Other medications are added or removed : Particularly other glucose-lowering agents Important considerations during dose changes: Never skip doses or double up if you miss an injectionfollow the specific guidance in your patient information leaflet For missed doses, each product has different instructions: Semaglutide (Ozempic/Wegovy): If within 5 days, take as soon as possible
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